Tuberin antibody (AA 1396-1496) (HRP)
Quick Overview for Tuberin antibody (AA 1396-1496) (HRP) (ABIN7173646)
Target
See all Tuberin (TSC2) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1396-1496
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human Tuberin protein (1396-1496AA)
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Isotype
- IgG
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anti-Tuberous Sclerosis 2 (TSC2) (AA 1776-1805) antibody
TSC2 Reactivity: Human WB, IF, IHC (p) Host: Rabbit Polyclonal RB13393 unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1611-1807) antibodyTSC2 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1601-1750) antibodyTSC2 Reactivity: Human, Mouse, Rat ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1776-1805) antibodyTSC2 Reactivity: Human ELISA, WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 900-1150) antibodyTSC2 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (pThr1462) antibodyTSC2 Reactivity: Human, Mouse, Rat ELISA, WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (pSer1387) antibodyTSC2 Reactivity: Human DB, IF Host: Rabbit Polyclonal RB11388 unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1397-1426) antibodyTSC2 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB42388 unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1396-1496) antibodyTSC2 Reactivity: Human ELISA, WB, IF Host: Rabbit Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (pThr927) antibodyTSC2 Reactivity: Mouse, Rat ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
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Alternative Name
- TSC2
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Background
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Background: In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. May also play a role in microtubule-mediated protein transport. Also stimulates the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5.
Aliases: FLJ43106 antibody, LAM antibody, OTTHUMP00000158940 antibody, OTTHUMP00000198394 antibody, OTTHUMP00000198395 antibody, PPP1R160 antibody, Protein phosphatase 1, regulatory subunit 160 antibody, TSC complex subunit 2 antibody, tsc2 antibody, TSC2_HUMAN antibody, TSC4 antibody, TSC4 gene, formerly antibody, TSC4, formerly antibody, Tuberin antibody, Tuberous sclerosis 2 antibody, Tuberous sclerosis 2 protein antibody, Tuberous sclerosis 2 protein homolog antibody
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UniProt
- P49815
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Pathways
- RTK Signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
Target
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