TWEAK antibody (AA 42-123)

Catalog No. ABIN7173794

Product Details anti-TWEAK Antibody

Target: TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))

Binding Specificity: AA 42-123

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TWEAK antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Tumor necrosis factor ligand superfamily member 12 protein (42-123AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TWEAK

Target: TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))

Alternative Name: TNFSF12 (TNFSF12 Products)

Synonyms: APO3L antibody, DR3LG antibody, TWEAK antibody, Apo3l antibody, Dr3l antibody, Dr3lg antibody, Tweak antibody, TNF superfamily member 12 antibody, tumor necrosis factor (ligand) superfamily, member 12 antibody, TNFSF12 antibody, Tnfsf12 antibody

Background:

Background: Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.

Aliases: APO 3 ligand antibody, APO 3L antibody, APO3 ligand antibody, APO3/DR3 ligand antibody, APO3L antibody, DR3LG antibody, MGC129581 antibody, MGC20669 antibody, secreted form antibody, TNF-related weak inducer of apoptosis antibody, TNF12_HUMAN antibody, TNFSF 12 antibody, Tnfsf12 antibody, TNFSF12 protein antibody, Tumor necrosis factor (ligand) superfamily member 12 antibody, Tumor necrosis factor ligand superfamily member 12 antibody, Tumor necrosis factor superfamily member 12 antibody, TWEAK antibody, UNQ181/PRO207 antibody

UniProt: O43508

Pathways: Apoptosis