USP4 antibody (AA 632-810) (HRP)

Catalog No. ABIN7174331

Product Details anti-USP4 Antibody (HRP)

Target: USP4 (Ubiquitin Specific Peptidase 4 (USP4))

Binding Specificity: AA 632-810

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP4 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ubiquitin carboxyl-terminal hydrolase 4 protein (632-810AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for USP4

Target: USP4 (Ubiquitin Specific Peptidase 4 (USP4))

Alternative Name: USP4 (USP4 Products)

Synonyms: UNP antibody, Unph antibody, F730026I20Rik antibody, Unp antibody, mKIAA4155 antibody, ubiquitin specific peptidase 4 antibody, ubiquitin specific peptidase 4 (proto-oncogene) antibody, USP4 antibody, Usp4 antibody

Background:

Background: Hydrolase that deubiquitinates target proteins such as the receptor ADORA2A, PDPK1 and TRIM21. Deubiquitination of ADORA2A increases the amount of functional receptor at the cell surface. May regulate mRNA splicing through deubiquitination of the U4 spliceosomal protein PRPF3. This may prevent its recognition by the U5 component PRPF8 thereby destabilizing interactions within the U4/U6.U5 snRNP. May also play a role in the regulation of quality control in the ER.

Aliases: Deubiquitinating enzyme 4 antibody, MGC149848 antibody, MGC149849 antibody, Proto oncogene antibody, Protooncogene antibody, Ubiquitin carboxyl terminal hydrolase 4 antibody, Ubiquitin carboxyl-terminal hydrolase 4 antibody, Ubiquitin specific peptidase 4 (proto oncogene) antibody, Ubiquitin specific peptidase 4 (protooncogene) antibody, Ubiquitin specific peptidase 4 antibody, Ubiquitin specific processing protease 4 antibody, Ubiquitin specific protease 4 (proto oncogene) antibody, Ubiquitin specific protease 4 (protooncogene) antibody, Ubiquitin specific protease 4 antibody, Ubiquitin specific protease proto oncogene antibody, Ubiquitin specific protease protooncogene antibody, Ubiquitin thioesterase 4 antibody, Ubiquitin thiolesterase 4 antibody, Ubiquitin-specific-processing protease 4 antibody, Ubiquitous nuclear protein homolog antibody, UBP4_HUMAN antibody, UNP antibody, UNPH antibody, USP 4 antibody, USP4 antibody

UniProt: Q13107