CACNA1H antibody (AA 260-360)

Catalog No. ABIN7175612

Product Details anti-CACNA1H Antibody

Target: CACNA1H (Calcium Channel, Voltage-Dependent, T Type, alpha 1H Subunit (CACNA1H))

Binding Specificity: AA 260-360

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNA1H antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Voltage-dependent T-type calcium channel subunit alpha-1H protein (260-360AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CACNA1H

Target: CACNA1H (Calcium Channel, Voltage-Dependent, T Type, alpha 1H Subunit (CACNA1H))

Alternative Name: CACNA1H (CACNA1H Products)

Synonyms: CACNA1HB antibody, Cav3.2 antibody, ECA6 antibody, EIG6 antibody, MNCb-1209 antibody, alpha13.2 antibody, calcium voltage-gated channel subunit alpha1 H antibody, calcium channel, voltage-dependent, T type, alpha 1H subunit antibody, CACNA1H antibody, Cacna1h antibody

Background:

Background: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1H gives rise to T-type calcium currents. T-type calcium channels belong to the \\\"low-voltage activated (LVA)\\\" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.

Aliases: Alpha1 3.2 antibody, Alpha13.2 antibody, CAC1H_HUMAN antibody, CACNA 1H antibody, CACNA1 H antibody, CACNA1 HB antibody, Cacna1h antibody, CACNA1HB antibody, Calcium channel alpha13.2 subunit antibody, Calcium channel voltage dependent T type alpha 1H subunit antibody, Calcium channel, voltage-dependent, T type, alpha 1Hb subunit antibody, Cav 3.2 antibody, Cav T.2 antibody, Cav3.2 antibody, CavT.2 antibody, EIG 6 antibody, EIG6 antibody, Low voltage activated calcium channel alpha 13.2 subunit antibody, Low voltage activated calcium channel alpha1 3.2 subunit antibody, Low-voltage-activated calcium channel alpha1 3.2 subunit antibody, MNCb 1209 antibody, T type Cav3.2 antibody, Voltage dependent t type calcium channel alpha 1H subunit antibody, Voltage gated calcium channel alpha subunit Cav 3.2 antibody, Voltage gated calcium channel alpha subunit Cav T.2 antibody, Voltage gated calcium channel alpha subunit Cav3.2 antibody, Voltage gated calcium channel alpha subunit CavT.2 antibody, Voltage-dependent T-type calcium channel subunit alpha-1H antibody, Voltage-gated calcium channel subunit alpha Cav3.2 antibody

UniProt: O95180

Pathways: C21-Steroid Hormone Metabolic Process