SLC7A6 antibody (AA 473-515) (HRP)

Catalog No. ABIN7175940

Product Details anti-SLC7A6 Antibody (HRP)

Target: SLC7A6 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 6 (SLC7A6))

Binding Specificity: AA 473-515

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC7A6 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Y+L amino acid transporter 2 protein (473-515AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SLC7A6

Target: SLC7A6 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 6 (SLC7A6))

Alternative Name: SLC7A6 (SLC7A6 Products)

Synonyms: id:ibd2834 antibody, LAT-2 antibody, LAT3 antibody, y+LAT-2 antibody, AI643885 antibody, solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 antibody, solute carrier family 7 member 6 antibody, solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 L homeolog antibody, solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 antibody, slc7a6 antibody, Slc7a6 antibody, SLC7A6 antibody, slc7a6.L antibody

Background:

Background: Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes. Reduces uptake of ornithine in retinal pigment epithelial (RPE) cells.

Aliases: SLC7A6 antibody, KIAA0245 antibody, Y+L amino acid transporter 2 antibody, Cationic amino acid transporter antibody, y+ system antibody, Solute carrier family 7 member 6 antibody, y(+)L-type amino acid transporter 2 antibody, Y+LAT2 antibody, y+LAT-2 antibody

UniProt: Q92536