Bcl-2 antibody (AA 5-205) (FITC)

Catalog No. ABIN7176966

The Rabbit Polyclonal anti-Bcl-2 antibody has been validated for . It is suitable to detect Bcl-2 in samples from Mouse.

Quick Overview for Bcl-2 antibody (AA 5-205) (FITC) (ABIN7176966)

Target: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Bcl-2 antibody is conjugated to FITC

Application: Please inquire

Product Details anti-Bcl-2 Antibody (FITC)

Binding Specificity: AA 5-205

Cross-Reactivity: Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Mouse Apoptosis regulator Bcl-2 protein (5-205AA)

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Bcl-2

Target: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Alternative Name: Bcl2

Background:

Background: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

Aliases: Bcl2 antibody, Bcl-2 antibody, Apoptosis regulator Bcl-2 antibody

UniProt: P10417

Pathways: MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling