STAT5B antibody (Ser731)

Catalog No. ABIN7180086

The Rabbit Polyclonal anti-STAT5B antibody is suitable to detect STAT5B in samples from Human. It has been validated for WB, IHC and ELISA.

Quick Overview for STAT5B antibody (Ser731) (ABIN7180086)

Target: STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAT5B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-STAT5B Antibody

Binding Specificity: Ser731

Purpose: STAT5B (Ab-731) Antibody

Cross-Reactivity: Mouse, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized non-phosphopeptide derived from Human STAT5B around the phosphorylation site of serine 731(A-P-S-P-A).

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for STAT5B

Target: STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))

Alternative Name: STAT5B

Background:

Background: Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription.

Zsuzsanna S. Nagy, J. Leukoc. Biol., Oct 2002, 72: 819.
Stanislaw M. Stepkowski, Blood, Jan 2002, 99: 680 - 689.
Salvador Aznar Benitah, Mol. Biol. Cell, Jan 2003, 14: 40.

Aliases: Signal transducer and activator of transcription 5B antibody, STA5B_HUMAN antibody, STAT5 antibody, Stat5b antibody, Transcription factor STAT5B antibody

UniProt: P51692

Pathways: JAK-STAT Signaling, RTK Signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation