SERPIND1 antibody

Catalog No. ABIN7183624

Product Details anti-SERPIND1 Antibody

Target: SERPIND1 (serpin Peptidase Inhibitor, Clade D (Heparin Cofactor), Member 1 (SERPIND1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPIND1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human Heparin Cofactor II.

Isotype: IgG

Application Details

Application Notes: IHC:1:50-1:100, IF:1:100-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SERPIND1

Target: SERPIND1 (serpin Peptidase Inhibitor, Clade D (Heparin Cofactor), Member 1 (SERPIND1))

Alternative Name: SERPIND1 (SERPIND1 Products)

Synonyms: D22S673 antibody, HC2 antibody, HCF2 antibody, HCII antibody, HLS2 antibody, LS2 antibody, THPH10 antibody, serpind1 antibody, MGC53936 antibody, rls2var1 antibody, AA985900 antibody, AI303446 antibody, Hcf2 antibody, serpin family D member 1 antibody, serpin peptidase inhibitor, clade D (heparin cofactor), member 1 L homeolog antibody, serpin peptidase inhibitor, clade D (heparin cofactor), member 1 antibody, serine (or cysteine) peptidase inhibitor, clade D, member 1 antibody, SERPIND1 antibody, serpind1.L antibody, Serpind1 antibody, serpind1 antibody

Background:

Background: Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner. Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils.

Blinder M.A., Biochemistry 27:752-759(1988).
Herzog R., Biochemistry 30:1350-1357(1991).
Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004).

Aliases: D22S673 antibody, HC II antibody, HC-II antibody, HC2 antibody, HCF2 antibody, HEP2_HUMAN antibody, Heparin cofactor 2 antibody, Heparin cofactor II antibody, HLS2 antibody, Leuserpin 2 antibody, LS2 antibody, Protease inhibitor leuserpin 2 antibody, Protease inhibitor leuserpin-2 antibody, serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1 antibody, Serpin D1 antibody, serpin peptidase inhibitor, clade D (heparin cofactor), member 1 antibody, SERPIND1 antibody, THPH10 antibody

UniProt: P05546