Podocin antibody

Catalog No. ABIN7342489

Product Details anti-Podocin Antibody

Target: Podocin (NPHS2) (Nephrosis 2, Idiopathic, Steroid-Resistant (Podocin) (NPHS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Podocin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human, Mouse, Rat

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human NPHS2

Isotype: IgG

Application Details

Application Notes: ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Podocin

Target: Podocin (NPHS2) (Nephrosis 2, Idiopathic, Steroid-Resistant (Podocin) (NPHS2))

Alternative Name: NPHS2 (NPHS2 Products)

Synonyms: PDCN antibody, SRN1 antibody, AI790225 antibody, podocin antibody, nephrosis 2, podocin antibody, NPHS2, podocin antibody, Nphs2 antibody, NPHS2 antibody

Background:

Background: This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined.

Aliases: nephrosis 2 antibody, Nephrosis 2, idiopathic, steroid resistant (podocin) antibody, nephrosis 2, idiopathic, steroid resistant antibody, NPHS2 antibody, NPHS2 gene antibody, PDCN antibody, PODO_HUMAN antibody, Podocin antibody, SRN1 antibody

UniProt: Q9NP85