SEZ6L antibody

Catalog No. ABIN7192337

Product Details anti-SEZ6L Antibody

Target: SEZ6L (Seizure Related 6 Homolog Like (SEZ6L))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEZ6L antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human SEZ6L

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:2000, IHC:1:25-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SEZ6L

Target: SEZ6L (Seizure Related 6 Homolog Like (SEZ6L))

Alternative Name: SEZ6L (SEZ6L Products)

Synonyms: RGD1563628 antibody, AI843918 antibody, AIG1 antibody, AW539724 antibody, Acig1 antibody, BSRP-B antibody, mKIAA0927 antibody, seizure related 6 homolog like antibody, SEZ6L antibody, Sez6l antibody

Background:

Background: SEZ6L (seizure related 6 homolog-like) is a 1,024 amino acid single-pass type I membrane protein that localizes to the endoplasmic reticulum. Widely expressed, SEZ6L is a candidate tumor suppressor gene and may contribute to specialized endoplasmic reticulum functions in neurons. SEZ6L contains three CUB domains and five sushi (CCP/SCR) domains, which may be involved in protein-protein interactions and signal transduction. The gene encoding SEZ6L is located on human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.

Aliases: SEZ6L antibody, KIAA0927 antibody, UNQ2542/PRO6094Seizure 6-like protein antibody

UniProt: Q9BYH1