SIGLEC8 antibody

Catalog No. ABIN7192372

This Rabbit Polyclonal antibody specifically detects SIGLEC8 in IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for SIGLEC8 antibody (ABIN7192372)

Target: SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIGLEC8 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-SIGLEC8 Antibody

Purpose: SIGLEC8 Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human SIGLEC8

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SIGLEC8

Target: SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))

Alternative Name: SIGLEC8

Background:

Background: Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM, MIM 603492) that mediates an association with SLAM-associated protein (SAP, MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).

Aliases: CD329 antigen antibody, CDw329 antibody, SAF 2 antibody, SAF-2 antibody, SAF2 antibody, Sialic acid binding Ig like lectin 8 antibody, Sialic acid-binding Ig-like lectin 8 antibody, Sialoadhesin family member 2 antibody, SIGL8_HUMAN antibody, Siglec 8 antibody, Siglec-8 antibody, SIGLEC8 antibody, SIGLEC8L antibody

UniProt: Q9NYZ4