SIGLEC8 antibody
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- Target See all SIGLEC8 Antibodies
- SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SIGLEC8 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- Antigen affinity purification
- Immunogen
- Synthetic peptide of Human SIGLEC8
- Isotype
- IgG
- Top Product
- Discover our top product SIGLEC8 Primary Antibody
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- Application Notes
- ELISA:1:2000-1:5000, IHC:1:25-1:100,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
- Alternative Name
- SIGLEC8 (SIGLEC8 Products)
- Background
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Background: Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM, MIM 603492) that mediates an association with SLAM-associated protein (SAP, MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).
Aliases: CD329 antigen antibody, CDw329 antibody, SAF 2 antibody, SAF-2 antibody, SAF2 antibody, Sialic acid binding Ig like lectin 8 antibody, Sialic acid-binding Ig-like lectin 8 antibody, Sialoadhesin family member 2 antibody, SIGL8_HUMAN antibody, Siglec 8 antibody, Siglec-8 antibody, SIGLEC8 antibody, SIGLEC8L antibody
- UniProt
- Q9NYZ4
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