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SIGLEC8 antibody

SIGLEC8 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7192372
  • Target See all SIGLEC8 Antibodies
    SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
    Reactivity
    • 36
    • 5
    • 1
    Human
    Host
    • 27
    • 8
    • 1
    Rabbit
    Clonality
    • 29
    • 7
    Polyclonal
    Conjugate
    • 23
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIGLEC8 antibody is un-conjugated
    Application
    • 27
    • 15
    • 14
    • 6
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human
    Purification
    Antigen affinity purification
    Immunogen
    Synthetic peptide of Human SIGLEC8
    Isotype
    IgG
    Top Product
    Discover our top product SIGLEC8 Primary Antibody
  • Application Notes
    ELISA:1:2000-1:5000, IHC:1:25-1:100,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
    Alternative Name
    SIGLEC8 (SIGLEC8 Products)
    Background

    Background: Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM, MIM 603492) that mediates an association with SLAM-associated protein (SAP, MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).

    Aliases: CD329 antigen antibody, CDw329 antibody, SAF 2 antibody, SAF-2 antibody, SAF2 antibody, Sialic acid binding Ig like lectin 8 antibody, Sialic acid-binding Ig-like lectin 8 antibody, Sialoadhesin family member 2 antibody, SIGL8_HUMAN antibody, Siglec 8 antibody, Siglec-8 antibody, SIGLEC8 antibody, SIGLEC8L antibody

    UniProt
    Q9NYZ4
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