ATP1B3 antibody (AA 57-279)

Catalog No. ABIN7193737

Product Details anti-ATP1B3 Antibody

Target: ATP1B3 (ATPase, Na+/K+ Transporting, beta 3 Polypeptide (ATP1B3))

Binding Specificity: AA 57-279

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ATP1B3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purification: purified

Immunogen: Purified recombinant fragment of human CD298 (AA: extra 57-279) expressed in E. coli.

Clone: 2B3G10

Isotype: IgG1

Application Details

Application Notes: WB:1:500 - 1:2000, IHC:1:200 - 1:1000, FCM:1:200 - 1:400, ELISA:1:10000,

Restrictions: For Research Use only

Handling

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for ATP1B3

Target: ATP1B3 (ATPase, Na+/K+ Transporting, beta 3 Polypeptide (ATP1B3))

Alternative Name: CD298 (ATP1B3 Products)

Synonyms: ATPB-3 antibody, CD298 antibody, AA409958 antibody, AI664000 antibody, AW212096 antibody, NKAB3S antibody, atp1b3 antibody, cb714 antibody, fb13c07 antibody, wu:fb13c07 antibody, cb713 antibody, nakatpb antibody, wu:fa14a07 antibody, ATPase Na+/K+ transporting subunit beta 3 antibody, ATPase, Na+/K+ transporting, beta 3 polypeptide antibody, ATPase Na+/K+ transporting subunit beta 3 S homeolog antibody, ATPase, Na+/K+ transporting, beta 3b polypeptide antibody, ATPase, Na+/K+ transporting, beta 3a polypeptide antibody, ATP1B3 antibody, Atp1b3 antibody, atp1b3.S antibody, atp1b3b antibody, atp1b3a antibody

Background:

Description: The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2.

Aliases: ATP1B3, ATPB-3

Molecular Weight: 31.5 kDa

Gene ID: 483

Pathways: Thyroid Hormone Synthesis