ALMS1 antibody (AA 1530-1610)

Catalog No. ABIN7213562

The Rabbit Polyclonal anti-ALMS1 antibody is suitable to detect ALMS1 in samples from Human and Mouse. It has been validated for ELISA, WB, IHC and IF.

Quick Overview for ALMS1 antibody (AA 1530-1610) (ABIN7213562)

Target: ALMS1 (Alstrom Syndrome 1 (ALMS1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALMS1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ALMS1 Antibody

Binding Specificity: AA 1530-1610

Purpose: Rabbit Anti-ALMS1 Polyclonal Antibody

Specificity: ALMS1 Polyclonal Antibody detects endogenous levels of ALMS1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human ALMS1 at AA range: 1530-1610

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ALMS1

Target: ALMS1 (Alstrom Syndrome 1 (ALMS1))

Alternative Name: ALMS1

Background: ALMS1, KIAA0328, Alstrom syndrome protein 1ALMS1 encodes a protein containing a large tandem-repeat domain as well as additional low complexity regions. The encoded protein (ALMS1, centrosome and basal body associated protein) functions in microtubule organization, particularly in the formation and maintanance of cilia. Mutations ALMS1 cause Alstrom syndrome. There is a pseudogene for ALMS1 located adjacent in the same region of chromosome 2. Alternative splice variants have been described but their full length nature has not been determined.

Molecular Weight: 460kD

Gene ID: 7840

UniProt: Q8TCU4

Pathways: Sensory Perception of Sound, Carbohydrate Homeostasis, M Phase