Annexin a1 antibody (pTyr21)

Catalog No. ABIN7213354

The Rabbit Polyclonal anti-Annexin a1 antibody is suitable to detect Annexin a1 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for Annexin a1 antibody (pTyr21) (ABIN7213354)

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Annexin a1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Annexin a1 Antibody

Binding Specificity: pTyr21

Purpose: Rabbit Anti-Annexin I (phospho Tyr21) Polyclonal Antibody

Specificity: Phospho-Annexin I (Y21) Polyclonal Antibody detects endogenous levels of Annexin I protein only when phosphorylated at Y21.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Annexin I Phospho-Tyr21

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Annexin a1

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Alternative Name: Annexin I

Background: ANXA1, ANX1, LPC1, Annexin A1, Annexin I, Annexin-1, Calpactin II, Calpactin-2, Chromobindin-9, Lipocortin I, Phospholipase A2 inhibitory protein, p35ANXA1 encodes a membrane-localized protein that binds phospholipids. Annexin A1 inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of ANXA1 has been detected in multiple tumors.

Gene ID: 301

UniProt: P04083

Pathways: Hormone Transport