ATP6AP1 antibody (AA 421-470)

Catalog No. ABIN7232074

This Rabbit Polyclonal antibody specifically detects ATP6AP1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ATP6AP1 antibody (AA 421-470) (ABIN7232074)

Target: ATP6AP1 (ATPase, H+ Transporting, Lysosomal Accessory Protein 1 (ATP6AP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP6AP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ATP6AP1 Antibody

Binding Specificity: AA 421-470

Purpose: V-ATPase S1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of V-ATPase S1

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human V-ATPase S1 protein at AA range: 421-470

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for ATP6AP1

Target: ATP6AP1 (ATPase, H+ Transporting, Lysosomal Accessory Protein 1 (ATP6AP1))

Alternative Name: V-ATPase S1

Background: Rabbit Anti-V-ATPase S1 Polyclonal Antibody,V-type proton ATPase subunit S1, V-ATPase subunit S1, Protein XAP-3, V-ATPase Ac45 subunit, V-ATPase S1 accessory protein, Vacuolar proton pump subunit S1,ATP6AP1 encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of ATP6AP1 may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. This protein may also play a role in early development.,V-ATPase S1

Molecular Weight: observerd band 51kDa

Gene ID: 537

UniProt: Q15904

Pathways: Proton Transport, SARS-CoV-2 Protein Interactome