CD226 antibody (Internal Region)

Catalog No. ABIN7218330

The Rabbit Polyclonal anti-CD226 antibody (ABIN7218330) specifically detects CD226 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for CD226 antibody (Internal Region) (ABIN7218330)

Target: CD226

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD226 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CD226 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-DNAM-1 Polyclonal Antibody

Specificity: DNAM-1 Polyclonal Antibody detects endogenous levels of DNAM-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human DNAM-1

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CD226

Target: CD226

Alternative Name: DNAM-1

Background: CD226, DNAM1, CD226 antigen, DNAX accessory molecule 1, DNAM-1, CD226CD226 encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.

Molecular Weight: 38kD

Gene ID: 10666

UniProt: Q15762

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints