CD226 antibody

Catalog No. ABIN7219104

The Rabbit Polyclonal anti-CD226 antibody has been validated for WB, ELISA, IF and IHC (p). It is suitable to detect CD226 in samples from Human, Mouse and Monkey.

Quick Overview for CD226 antibody (ABIN7219104)

Target: CD226

Reactivity: Human, Mouse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD226 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CD226 Antibody

Purpose: DNAM-1 Polyclonal Antibody

Specificity: DNAM-1 Polyclonal Antibody detects endogenous levels of DNAM-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human DNAM-1 around the non-phosphorylation site of S329

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CD226

Target: CD226

Alternative Name: DNAM-1

Background: Rabbit Anti-DNAM-1 Polyclonal Antibody,CD226, DNAM1, CD226 antigen, DNAX accessory molecule 1, DNAM-1, CD antigen CD226,CD226 encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The CD226 Molecule mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.,CD226 antigen

Molecular Weight: observerd band 38kDa

Gene ID: 10666

UniProt: Q15762

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints