COL17A1 antibody (AA 1-80)

Catalog No. ABIN7219556

The Rabbit Polyclonal anti-COL17A1 antibody is suitable to detect COL17A1 in samples from Human and Mouse. It has been validated for ELISA and IHC (p).

Quick Overview for COL17A1 antibody (AA 1-80) (ABIN7219556)

Target: COL17A1 (Collagen, Type XVII, alpha 1 (COL17A1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COL17A1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-COL17A1 Antibody

Binding Specificity: AA 1-80

Purpose: COL17A1 Polyclonal Antibody

Specificity: COL17A1 Polyclonal Antibody detects endogenous levels of COL17A1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human COL17A1 at AA range: 1-80

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for COL17A1

Target: COL17A1 (Collagen, Type XVII, alpha 1 (COL17A1))

Alternative Name: COL17A1

Background: Rabbit Anti-COL17A1 Polyclonal Antibody,COL17A1, BP180, BPAG2, Collagen alpha-1(XVII) chain, 180 kDa bullous pemphigoid antigen 2, Bullous pemphigoid antigen 2,COL17A1 encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form.,Collagen alpha-1(XVII) chain

Gene ID: 1308

UniProt: Q9UMD9