C3AR1 antibody (AA 150-230)

Catalog No. ABIN7224804

The Rabbit Polyclonal anti-C3AR1 antibody is suitable to detect C3AR1 in samples from Human, Mouse and Rat. It has been validated for IHC, ELISA and IF.

Quick Overview for C3AR1 antibody (AA 150-230) (ABIN7224804)

Target: C3AR1 (Complement Component 3a Receptor 1 (C3AR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C3AR1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-C3AR1 Antibody

Binding Specificity: AA 150-230

Purpose: Rabbit Anti-C3aR Polyclonal Antibody

Specificity: C3aR Polyclonal Antibody detects endogenous levels of C3aR protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human C3aR at AA range: 150-230

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for C3AR1

Target: C3AR1 (Complement Component 3a Receptor 1 (C3AR1))

Alternative Name: C3aR

Background: C3AR1, AZ3B, C3R1, HNFAG09, C3a anaphylatoxin chemotactic receptor, C3AR, C3a-RC3a (complement C3a receptor 1) is an anaphylatoxin released during activation of the complement system. The protein encoded by C3AR1 is an orphan G protein-coupled receptor for C3a. Binding of C3a by the encoded receptor activates chemotaxis, granule enzyme release, superoxide anion production, and bacterial opsonization.

Gene ID: 719

UniProt: Q16581

Pathways: Complement System