CYFIP2 antibody (AA 1171-1220)

Catalog No. ABIN7226882

The Rabbit Polyclonal anti-CYFIP2 antibody is suitable to detect CYFIP2 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for CYFIP2 antibody (AA 1171-1220) (ABIN7226882)

Target: CYFIP2 (Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYFIP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CYFIP2 Antibody

Binding Specificity: AA 1171-1220

Purpose: Rabbit Anti-CYFIP2 Polyclonal Antibody

Specificity: CYFIP2 Polyclonal Antibody detects endogenous levels of CYFIP2.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from CYFIP2 at AA range: 1171-1220

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CYFIP2

Target: CYFIP2 (Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2))

Alternative Name: CYFIP2

Background: Cytoplasmic FMR1-interacting protein 2, p53-inducible protein 121CYFIP2 belongs to the CYFIP family and is involved in T-cell adhesion and p53-dependent induction of apoptosis. CYFIP2 mRNA is ubiquitously expressed and particularly abundant in the central nervous system. Recently, CYFIP2 was regarded as one of the ALS potential biomarkes in non-neural tissues from amyotrophic lateral sclerosis (ALS) patients that may have direct diagnostic and therapeutic implications to the disease.

Molecular Weight: 150kD,45kD

Gene ID: 26999

UniProt: Q96F07

Pathways: RTK Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity