DISP1 antibody (AA 270-350)

Catalog No. ABIN7228224

This Rabbit Polyclonal antibody specifically detects DISP1 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for DISP1 antibody (AA 270-350) (ABIN7228224)

Target: DISP1 (Dispatched Homolog 1 (DISP1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DISP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DISP1 Antibody

Binding Specificity: AA 270-350

Purpose: Rabbit Anti-DISP1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of DISP1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human DISP1 protein at AA range: 270-350

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DISP1

Target: DISP1 (Dispatched Homolog 1 (DISP1))

Alternative Name: DISP1

Background: Protein dispatched homolog 1The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. DISP1 is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo.

Molecular Weight: 167kD

Gene ID: 84976

UniProt: Q96F81

Pathways: Hedgehog Signaling