DISP1 antibody (AA 1325-1524)

Catalog No. ABIN7266798

The Rabbit Polyclonal anti-DISP1 antibody (ABIN7266798) specifically detects DISP1 in WB. The antibody is reactive with Human samples.

Quick Overview for DISP1 antibody (AA 1325-1524) (ABIN7266798)

Target: DISP1 (Dispatched Homolog 1 (DISP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DISP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DISP1 Antibody

Binding Specificity: AA 1325-1524

Purpose: DISP1 Rabbit pAb

Sequence: FVHPITHIHH CPCLQGRVKP AGMQNSLPRN FFLHPVQHIQ AQEKIGKTNV HSLQRSIEEH LPKMAEPSSF VCRSTGSLLK TCCDPENKQR ELCKNRDVSN LESSGGTENK AGGKVELSLS QTDASVNSEH FNQNEPKVLF NHLMGEAGCR SCPNNSQSCG RIVRVKCNSV DCQMPNMEAN VPAVLTHSEL SGESLLIKTL

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1325-1524 of human DISP1 (NP_116279.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DISP1

Target: DISP1 (Dispatched Homolog 1 (DISP1))

Alternative Name: DISP1

Background: The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo.,DISP1,DISPA,Signal Transduction,Neuroscience,DISP1

Molecular Weight: 170kDa

Gene ID: 84976

UniProt: Q96F81

Pathways: Hedgehog Signaling