FLT3LG antibody (C-Term)

Catalog No. ABIN7218546

The Rabbit Polyclonal anti-FLT3LG antibody (ABIN7218546) specifically detects FLT3LG in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for FLT3LG antibody (C-Term) (ABIN7218546)

Target: FLT3LG (Fms-Related tyrosine Kinase 3 Ligand (FLT3LG))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLT3LG antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FLT3LG Antibody

Binding Specificity: C-Term

Purpose: Rabbit Anti-Flt3-L Polyclonal Antibody

Specificity: Flt3-L Polyclonal Antibody detects endogenous levels of Flt3-L protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human Flt3-L

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FLT3LG

Target: FLT3LG (Fms-Related tyrosine Kinase 3 Ligand (FLT3LG))

Alternative Name: Flt3-L

Background: FLT3LG, Fms-related tyrosine kinase 3 ligand, Flt3 ligand, Flt3L, SL cytokineDendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE, MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al. 2010 [PubMed: 20933441]).

Molecular Weight: 26kD

Gene ID: 2323

UniProt: P49771

Pathways: RTK Signaling