GABRE antibody (Internal Region)

Catalog No. ABIN7217688

The Rabbit Polyclonal anti-GABRE antibody has been validated for WB and ELISA. It is suitable to detect GABRE in samples from Human.

Quick Overview for GABRE antibody (Internal Region) (ABIN7217688)

Target: GABRE (gamma-aminobutyric Acid (GABA) A Receptor, epsilon (GABRE))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRE antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GABRE Antibody

Binding Specificity: Internal Region

Purpose: GABAA Rε Polyclonal Antibody

Specificity: GABAA Rε Polyclonal Antibody detects endogenous levels of GABAA Rε protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human GABAA range: Repsilon

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for GABRE

Target: GABRE (gamma-aminobutyric Acid (GABA) A Receptor, epsilon (GABRE))

Alternative Name: GABAA Repsilon

Background: Rabbit Anti-GABAA Rε Polyclonal Antibody,GABRE, Gamma-aminobutyric acid receptor subunit epsilon, GABA(A) receptor subunit epsilon,The product of GABRE belongs to the ligand-gated ionic channel (TC 1. A. ) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in a cluster comprised of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively spliced transcript variants have been identified, but only one is thought to encode a protein.,Gamma-aminobutyric acid receptor subunit epsilon

Molecular Weight: observerd band 57kDa

Gene ID: 2564

UniProt: P78334

Pathways: Synaptic Membrane