ITGB1 antibody (pTyr795)

Catalog No. ABIN7221888

The Rabbit Polyclonal anti-ITGB1 antibody (ABIN7221888) specifically detects ITGB1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ITGB1 antibody (pTyr795) (ABIN7221888)

Target: ITGB1 (Integrin beta 1 (ITGB1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ITGB1 Antibody

Binding Specificity: pTyr795

Purpose: Rabbit Anti-Integrin β1 (phospho Tyr795) Polyclonal Antibody

Specificity: Phospho-Integrin β1 (Y795) Polyclonal Antibody detects endogenous levels of Integrin β1 protein only when phosphorylated at Y795.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Integrin beta1 Phospho-Tyr795

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ITGB1

Target: ITGB1 (Integrin beta 1 (ITGB1))

Alternative Name: Integrin beta1

Background: ITGB1, FNRB, MDF2, MSK12, Integrin beta-1, Fibronectin receptor subunit beta, VLA-4 subunit beta, CD antigen CD29Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. ITGB1 encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.

Molecular Weight: 140kD

Gene ID: 3688

UniProt: P05556

Pathways: Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome