IFI16 antibody (AA 700-780)

Catalog No. ABIN7221668

The Rabbit Polyclonal anti-IFI16 antibody (ABIN7221668) specifically detects IFI16 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for IFI16 antibody (AA 700-780) (ABIN7221668)

Target: IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFI16 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IFI16 Antibody

Binding Specificity: AA 700-780

Purpose: Rabbit Anti-IFI-16 Polyclonal Antibody

Specificity: IFI-16 Polyclonal Antibody detects endogenous levels of IFI-16 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human IFI-16 at AA range: 700-780

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IFI16

Target: IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))

Alternative Name: IFI-16

Background: IFI16, IFNGIP1, Gamma-interferon-inducible protein 16, Ifi-16, Interferon-inducible myeloid differentiation transcriptional activatorIFI16 encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 88kD

Gene ID: 3428

UniProt: Q16666

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Autophagy, Inflammasome