IL2RG antibody (Internal Region)

Catalog No. ABIN7218292

This Rabbit Polyclonal antibody specifically detects IL2RG in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for IL2RG antibody (Internal Region) (ABIN7218292)

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL2RG antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL2RG Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-IL-2Rγ Polyclonal Antibody

Specificity: IL-2Rγ Polyclonal Antibody detects endogenous levels of IL-2Rγ protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human IL-2Rgamma

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IL2RG

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Alternative Name: IL-2Rgamma

Background: IL2RG, Cytokine receptor common subunit gamma, Interleukin-2 receptor subunit gamma, IL-2 receptor subunit gamma, IL-2R subunit gamma, IL-2RG, gammaC, p64, CD132Cytokine receptor common subunit gamma encoded by IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.

Molecular Weight: 40kD

Gene ID: 3561

UniProt: P31785

Pathways: JAK-STAT Signaling, Growth Factor Binding