LSM2 antibody (AA 40-120)

Catalog No. ABIN7229464

The Rabbit Polyclonal anti-LSM2 antibody (ABIN7229464) specifically detects LSM2 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for LSM2 antibody (AA 40-120) (ABIN7229464)

Target: LSM2 (LSM2 Homolog, U6 Small Nuclear RNA Associated (LSM2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LSM2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-LSM2 Antibody

Binding Specificity: AA 40-120

Purpose: Rabbit Anti-LSM2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of LSM2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human LSM2 protein at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for LSM2

Target: LSM2 (LSM2 Homolog, U6 Small Nuclear RNA Associated (LSM2))

Alternative Name: LSM2

Background: U6 snRNA-associated Sm-like protein LSm2, Protein G7b, Small nuclear ribonuclear protein D homolog, snRNP core Sm-like protein Sm-x5LSM2 (LSM2 Homolog, U6 Small Nuclear RNA And MRNA Degradation Associated) is a Protein Coding gene. Diseases associated with LSM2 include Spinal Muscular Atrophy and Rheumatic Disease. Among its related pathways are Translational Control and mRNA Splicing - Major Pathway. LSM2 encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 19.

Molecular Weight: 10kD

Gene ID: 57819

UniProt: Q9Y333

Pathways: Ribonucleoprotein Complex Subunit Organization