M6PR antibody

Catalog No. ABIN7229748

The Rabbit Polyclonal anti-M6PR antibody is suitable to detect M6PR in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for M6PR antibody (ABIN7229748)

Target: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This M6PR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-M6PR Antibody

Purpose: Rabbit Anti-MPRD Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MPRD protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MPRD protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for M6PR

Target: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Alternative Name: MPRD

Background: Cation-dependent mannose-6-phosphate receptor, CD Man-6-P receptor, CD-MPR, 46 kDa mannose 6-phosphate receptor, MPR 46M6PR encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The Mannose-6-Phosphate Receptor, Cation Dependent functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X.

Molecular Weight: 30kD

Gene ID: 4074

UniProt: P20645