MCU antibody (Internal Region)

Catalog No. ABIN7225790

The Rabbit Polyclonal anti-MCU antibody is suitable to detect MCU in samples from Human and Mouse. It has been validated for ELISA, IHC and IF.

Quick Overview for MCU antibody (Internal Region) (ABIN7225790)

Target: MCU (Mitochondrial Calcium Uniporter (MCU))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCU antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MCU Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-CCDC109A Polyclonal Antibody

Specificity: CCDC109A Polyclonal Antibody detects endogenous levels of CCDC109A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human CCDC109A

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MCU

Target: MCU (Mitochondrial Calcium Uniporter (MCU))

Alternative Name: CCDC109A

Background: MCU, C10orf42, CCDC109A, Calcium uniporter protein, mitochondrial, Coiled-coil domain-containing protein 109AMCU (mitochondrial calcium uniporter) encodes a calcium transporter that localizes to the mitochondrial inner membrane. The encoded protein interacts with mitochondrial calcium uptake 1. Alternative splicing results in multiple transcript variants.

Gene ID: 90550

UniProt: Q8NE86

Pathways: Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis