Recombinant MCU antibody (AA 300-350)

Catalog No. ABIN7795789

The Rabbit Monoclonal anti-MCU antibody (Clone BLR355N) (ABIN7795789) specifically detects MCU in IHC, WB, ICC and IP. The antibody is reactive with Human and Mouse samples.

Quick Overview for Recombinant MCU antibody (AA 300-350) (ABIN7795789)

Target: MCU (Mitochondrial Calcium Uniporter (MCU))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MCU antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Clone: BLR355N

Product Details anti-MCU Antibody

Binding Specificity: AA 300-350

Purpose: Rabbit anti-MCU Recombinant Monoclonal Antibody [BLR355N]

Purification: Purified

Immunogen: between 300 and 350

Isotype: IgG

Application Details

Application Notes: WB,11,000,ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,IP,6 μL/mg lysate

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1000 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for MCU

Target: MCU (Mitochondrial Calcium Uniporter (MCU))

Alternative Name: MCU

Background: MCU is a channel-forming and calcium-conducting subunit of the mitochondrial inner membrane calcium uniporter complex (uniplex), which mediates calcium uptake into the mitochondrial matrix. MCU is involved in several processes, including cellular response to calcium ion starvation, positive regulation of mitochondrial calcium ion concentration, and positive regulation of mitochondrial fission. [taken from NCBI Entrez Gene (Gene ID: 90550)].

Gene ID: 90550

UniProt: Q8NE86

Pathways: Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis