Myosin VIIA antibody (AA 830-910)

Catalog No. ABIN7229866

The Rabbit Polyclonal anti-Myosin VIIA antibody is suitable to detect Myosin VIIA in samples from Human and Mouse. It has been validated for ELISA and WB.

Quick Overview for Myosin VIIA antibody (AA 830-910) (ABIN7229866)

Target: Myosin VIIA (MYO7A)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myosin VIIA antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-Myosin VIIA Antibody

Binding Specificity: AA 830-910

Purpose: Rabbit Anti-MYO7A Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MYO7A protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MYO7A protein at AA range: 830-910

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Myosin VIIA

Target: Myosin VIIA (MYO7A)

Alternative Name: MYO7A

Background: Unconventional myosin-VIIaMYO7A (Myosin VIIA) is a Protein Coding gene. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics and Actin Nucleation by ARP-WASP Complex. MYO7A is a member of the myosin gene family. Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. MYO7A encodes an unconventional myosin with a very short tail. Defects in MYO7A are associated with the mouse shaker-1 phenotype and the human Usher syndrome 1B which are characterized by deafness, reduced vestibular function, and (in human) retinal degeneration. Alternative splicing results in multiple transcript variants.

Molecular Weight: 243kD

Gene ID: 4647

UniProt: Q13402

Pathways: Sensory Perception of Sound