NEUROD1 antibody

Catalog No. ABIN7222706

The Rabbit Polyclonal anti-NEUROD1 antibody is suitable to detect NEUROD1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for NEUROD1 antibody (ABIN7222706)

Target: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEUROD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-NEUROD1 Antibody

Purpose: Rabbit Anti-Neuro D Polyclonal Antibody

Specificity: Neuro D Polyclonal Antibody detects endogenous levels of Neuro D protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Neuro D around the non-phosphorylation site of S274

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NEUROD1

Target: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Alternative Name: Neuro D

Background: NEUROD1, BHLHA3, NEUROD, Neurogenic differentiation factor 1, NeuroD, NeuroD1, Class A basic helix-loop-helix protein 3, bHLHa3NEUROD1 encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus.

Molecular Weight: 36kD

Gene ID: 4760

UniProt: Q13562

Pathways: Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis