NKX3-1 antibody (AA 1-80)

Catalog No. ABIN7216100

The Rabbit Polyclonal anti-NKX3-1 antibody is suitable to detect NKX3-1 in samples from Human and Mouse. It has been validated for IHC, WB, ELISA and IF.

Quick Overview for NKX3-1 antibody (AA 1-80) (ABIN7216100)

Target: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKX3-1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-NKX3-1 Antibody

Binding Specificity: AA 1-80

Purpose: Rabbit Anti-Nkx-3.1 Polyclonal Antibody

Specificity: Nkx-3.1 Polyclonal Antibody detects endogenous levels of Nkx-3.1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human Nkx-3.1 at AA range: 1-80

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NKX3-1

Target: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Alternative Name: Nkx-3.1

Background: NKX3-1, NKX3.1, NKX3A, Homeobox protein Nkx-3.1, Homeobox protein NK-3 homolog ANKX3-1 encodes a homeobox-containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of NKX3-1 is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of NKX3-1.

Molecular Weight: 38kD

Gene ID: 4824

UniProt: Q99801

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus