POLG antibody

Catalog No. ABIN7228278

The Rabbit Polyclonal anti-POLG antibody is suitable to detect POLG in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for POLG antibody (ABIN7228278)

Target: POLG (Polymerase (DNA Directed), gamma (POLG))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLG antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-POLG Antibody

Purpose: Rabbit Anti-DPOG1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of DPOG1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human DPOG1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for POLG

Target: POLG (Polymerase (DNA Directed), gamma (POLG))

Alternative Name: DPOG1

Background: DNA polymerase subunit gamma-1, Mitochondrial DNA polymerase catalytic subunit, PolG-alphaPOLG (DNA Polymerase Gamma, Catalytic Subunit) is a Protein Coding gene. Diseases associated with POLG include Mitochondrial Dna Depletion Syndrome 4A and Progressive External Ophthalmoplegia, Autosomal Recessive 1. Among its related pathways are DNA Damage and Metabolism.

Molecular Weight: 136kD

Gene ID: 5428

UniProt: P54098