PGAP1 antibody (AA 40-120)

Catalog No. ABIN7213856

The Rabbit Polyclonal anti-PGAP1 antibody (ABIN7213856) specifically detects PGAP1 in WB and ELISA. The antibody is reactive with Human, Mouse, Rat and Monkey samples.

Quick Overview for PGAP1 antibody (AA 40-120) (ABIN7213856)

Target: PGAP1 (Post-GPI Attachment To Proteins 1 (PGAP1))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PGAP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PGAP1 Antibody

Binding Specificity: AA 40-120

Purpose: Rabbit Anti-BST-1 Polyclonal Antibody

Specificity: BST-1 Polyclonal Antibody detects endogenous levels of BST-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human BST-1 at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PGAP1

Target: PGAP1 (Post-GPI Attachment To Proteins 1 (PGAP1))

Alternative Name: BST-1

Background: BST1, ADP-ribosyl cyclase 2, Bone marrow stromal antigen 1, BST-1, Cyclic ADP-ribose hydrolase 2, cADPr hydrolase 2, CD antigen CD157Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33 % similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.

Molecular Weight: 34kD

Gene ID: 683

UniProt: Q10588

Pathways: Sensory Perception of Sound, Inositol Metabolic Process