PPP2R4 antibody

Catalog No. ABIN7230832

The Rabbit Polyclonal anti-PPP2R4 antibody is suitable to detect PPP2R4 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for PPP2R4 antibody (ABIN7230832)

Target: PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PPP2R4 Antibody

Purpose: Rabbit Anti-PTPA Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PTPA protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PTPA protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PPP2R4

Target: PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))

Alternative Name: PTPA

Background: Serine/threonine-protein phosphatase 2A activator, PP2A, subunit B', PR53 isoform, Phosphotyrosyl phosphatase activator, PTPA, Serine/threonine-protein phosphatase 2A regulatory subunit 4, Serine/threonine-protein phosphatase 2A regulatory subunit B'PTPA (Protein Phosphatase 2 Phosphatase Activator) is a Protein Coding gene. Diseases associated with PTPA include Apical Myocardial Infarction and Leukemia, Acute Myeloid. Among its related pathways are DNA Damage and Regulation of CFTR activity (norm and CF). PTPA encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 39kD

Gene ID: 5524

UniProt: Q15257

Pathways: PI3K-Akt Signaling, M Phase, Hepatitis C, Toll-Like Receptors Cascades