Serotonin Receptor 6 antibody (AA 190-270)

Catalog No. ABIN7221626

This Rabbit Polyclonal antibody specifically detects Serotonin Receptor 6 in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Serotonin Receptor 6 antibody (AA 190-270) (ABIN7221626)

Target: Serotonin Receptor 6 (HTR6)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Serotonin Receptor 6 Antibody

Binding Specificity: AA 190-270

Purpose: SR-6 Polyclonal Antibody

Specificity: SR-6 Polyclonal Antibody detects endogenous levels of SR-6 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human SR-6 at AA range: 190-270

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Serotonin Receptor 6

Target: Serotonin Receptor 6 (HTR6)

Alternative Name: SR-6

Background: Rabbit Anti-SR-6 Polyclonal Antibody,HTR6, 5-hydroxytryptamine receptor 6, 5-HT-6, 5-HT6, Serotonin receptor 6,HTR6 encodes 5-hydroxytryptamine receptor 6 that belongs to the seven-transmembrane G protein-coupled receptor family of proteins. The encoded protein couples with the Gs alpha subunit and stimulates adenylate cyclase to activate the cyclic AMP-dependent signaling pathway. This receptor is thought to regulate cholinergic neuronal transmission in the brain. Several antidepressants and antipsychotic drugs have a high affinity for this receptor.,5-hydroxytryptamine receptor 6

Molecular Weight: observerd band 47kDa

Gene ID: 3362

UniProt: P50406

Pathways: JAK-STAT Signaling