SAA1 antibody

Catalog No. ABIN7231242

The Rabbit Polyclonal anti-SAA1 antibody (ABIN7231242) specifically detects SAA1 in ELISA and WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for SAA1 antibody (ABIN7231242)

Target: SAA1 (Serum Amyloid A1 (SAA1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAA1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-SAA1 Antibody

Purpose: Rabbit Anti-SAA1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SAA1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human SAA1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SAA1

Target: SAA1 (Serum Amyloid A1 (SAA1))

Alternative Name: SAA1

Background: Serum amyloid A-1 protein, SAA, Amyloid protein A, Amyloid fibril protein AASAA1 gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.

Molecular Weight: 13kD

Gene ID: 6288

UniProt: P0DJI8

Pathways: Toll-Like Receptors Cascades