SOD1 antibody (AA 280-360)

Catalog No. ABIN7221724

This Rabbit Polyclonal antibody specifically detects SOD1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SOD1 antibody (AA 280-360) (ABIN7221724)

Target: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SOD1 Antibody

Binding Specificity: AA 280-360

Purpose: Rabbit Anti-ALS Polyclonal Antibody

Specificity: ALS Polyclonal Antibody detects endogenous levels of ALS protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human ALS at AA range: 280-360

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SOD1

Target: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Alternative Name: ALS

Background: IGFALS, ALS, Insulin-like growth factor-binding protein complex acid labile subunit, ALSThe protein encoded by IGFALS is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene.

Molecular Weight: 66kD

Gene ID: 3483

UniProt: P35858

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis