TRF2 antibody (AA 130-210)

Catalog No. ABIN7231756

This Rabbit Polyclonal antibody specifically detects TRF2 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for TRF2 antibody (AA 130-210) (ABIN7231756)

Target: TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TRF2 Antibody

Binding Specificity: AA 130-210

Purpose: Rabbit Anti-TERF2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of TERF2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human TERF2 protein at AA range: 130-210

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TRF2

Target: TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

Alternative Name: TERF2

Background: Telomeric repeat-binding factor 2 , TTAGGG repeat-binding factor 2, Telomeric DNA-binding proteinTERF2 encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.

Molecular Weight: 55kD

Gene ID: 7014

UniProt: Q15554

Pathways: Cell Division Cycle, Telomere Maintenance