Thrombomodulin antibody (AA 500-580)

Catalog No. ABIN7224688

This Rabbit Polyclonal antibody specifically detects Thrombomodulin in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Thrombomodulin antibody (AA 500-580) (ABIN7224688)

Target: Thrombomodulin (THBD)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Thrombomodulin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Thrombomodulin Antibody

Binding Specificity: AA 500-580

Purpose: Rabbit Anti-CD141 Polyclonal Antibody

Specificity: CD141 Polyclonal Antibody detects endogenous levels of CD141 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human CD141 at AA range: 500-580

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Thrombomodulin

Target: Thrombomodulin (THBD)

Alternative Name: CD141

Background: THBD, THRM, Thrombomodulin, TM, Fetomodulin, CD antigen CD141The protein encoded by this intronless gene THBD (thrombomodulin) is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in THBD are a cause of thromboembolic disease, also known as inherited thrombophilia.

Molecular Weight: 100kD

Gene ID: 7056

UniProt: P07204