TP53BP1 antibody (pSer6)

Catalog No. ABIN7224784

The Rabbit Polyclonal anti-TP53BP1 antibody is suitable to detect TP53BP1 in samples from Human, Mouse, Rat and Monkey. It has been validated for IHC, WB, ELISA and IF.

Quick Overview for TP53BP1 antibody (pSer6) (ABIN7224784)

Target: TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TP53BP1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-TP53BP1 Antibody

Binding Specificity: pSer6

Purpose: Rabbit Anti-53BP1 (phospho Ser6) Polyclonal Antibody

Specificity: Phospho-53BP1 (S6) Polyclonal Antibody detects endogenous levels of 53BP1 protein only when phosphorylated at S6.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human 53BP1 Phospho-Ser6

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TP53BP1

Target: TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

Alternative Name: 53BP1

Background: TP53BP1, Tumor suppressor p53-binding protein 1, 53BP1, p53-binding protein 1, p53BP1TP53BP1 (Tumor Protein P53 Binding Protein 1) is a Protein Coding gene. Diseases associated with TP53BP1 include riddle syndrome and ataxia-telangiectasia. Among its related pathways are DNA Damage and ATM Pathway. GO annotations related to this gene include sequence-specific DNA binding and p53 binding.

Molecular Weight: 213kD

Gene ID: 7158

UniProt: Q12888

Pathways: DNA Damage Repair