TP53BP1 antibody (pSer25)

Catalog No. ABIN7224786

This anti-TP53BP1 antibody is a Rabbit Polyclonal antibody detecting TP53BP1 in ELISA, IF and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for TP53BP1 antibody (pSer25) (ABIN7224786)

Target: TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TP53BP1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TP53BP1 Antibody

Binding Specificity: pSer25

Purpose: 53BP1 (phospho Ser25) Polyclonal Antibody

Specificity: Phospho-53BP1 (S25) Polyclonal Antibody detects endogenous levels of 53BP1 protein only when phosphorylated at S25.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human 53BP1 Phospho-Ser25

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for TP53BP1

Target: TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

Alternative Name: 53BP1

Background: Rabbit Anti-53BP1 (phospho Ser25) Polyclonal Antibody,TP53BP1, Tumor suppressor p53-binding protein 1, 53BP1, p53-binding protein 1, p53BP1,TP53BP1 (Tumor Protein P53 Binding Protein 1) is a Protein Coding gene. Diseases associated with TP53BP1 include riddle syndrome and ataxia-telangiectasia. Among its related pathways are DNA Damage and ATM Pathway. GO annotations related to this gene include sequence-specific DNA binding and p53 binding.,Tumor suppressor p53-binding protein 1

Gene ID: 7158

UniProt: Q12888

Pathways: DNA Damage Repair