VPS4B antibody

Catalog No. ABIN7232116

This Rabbit Polyclonal antibody specifically detects VPS4B in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for VPS4B antibody (ABIN7232116)

Target: VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS4B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-VPS4B Antibody

Purpose: Rabbit Anti-VPS4B Polyclonal Antibody

Specificity: The antibody detects endogenous levels of VPS4B protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human VPS4B protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for VPS4B

Target: VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))

Alternative Name: VPS4B

Background: Vacuolar protein sorting-associated protein 4B, Cell migration-inducing gene 1 protein, Suppressor of K(+) transport growth defect 1, Protein SKD1VPS4B (Vacuolar Protein Sorting 4 Homolog B) is a Protein Coding gene. Diseases associated with VPS4B include Dentin Dysplasia, Type I, With Microdontia And Misshapen Teeth and Dentin Dysplasia. Among its related pathways are HIV Life Cycle and Budding and maturation of HIV virion. The protein encoded by VPS4B is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog.

Molecular Weight: 48kD

Gene ID: 9525

UniProt: O75351

Pathways: Microtubule Dynamics, CXCR4-mediated Signaling Events