Integrin beta 2 antibody

Catalog No. ABIN7232345

The Mouse Monoclonal anti-Integrin beta 2 antibody has been validated for FACS, WB, IHC, IP and Func. It is suitable to detect Integrin beta 2 in samples from Human.

Quick Overview for Integrin beta 2 antibody (ABIN7232345)

Target: Integrin beta 2 (ITGB2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin beta 2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Functional Studies (Func)

Clone: MEM48

Product Details anti-Integrin beta 2 Antibody

Purpose: Anti-Human CD18 Monoclonal Antibody, Azide Free Clone MEM48

Specificity: Recognizes the CD18 Molecule, a 95 kDa integrin molecule (β2 integrin) that forms the common beta chain of the CD11/CD18 heterodimer integrins.

Immunogen: Leucocytes from an LGL - type leukaemia,Sp 2/0 - Ag 14 myeloma cell line

Isotype: IgG1 kappa

Biological Activity Comment: Identification of CD18+ leukocytes. Blocks cell-cell interaction.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

Target Details for Integrin beta 2

Target: Integrin beta 2 (ITGB2)

Alternative Name: CD18

Background: Integrin b 2

Pathways: NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation