ASCL1 antibody (AA 77-236)

Catalog No. ABIN7265373

The Rabbit Polyclonal anti-ASCL1 antibody (ABIN7265373) specifically detects ASCL1 in WB. The antibody is reactive with Human samples.

Quick Overview for ASCL1 antibody (AA 77-236) (ABIN7265373)

Target: ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASCL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ASCL1 Antibody

Binding Specificity: AA 77-236

Purpose: AscL1 Rabbit pAb

Sequence: GGHKSAPKQV KRQRSSSPEL MRCKRRLNFS GFGYSLPQQQ PAAVARRNER ERNRVKLVNL GFATLREHVP NGAANKKMSK VETLRSAVEY IRALQQLLDE HDAVSAAFQA GVLSPTISPN YSNDLNSMAG SPVSSYSSDE GSYDPLSPEE QELLDFTNWF

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 77-236 of human AscL1 (NP_004307.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ASCL1

Target: ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))

Alternative Name: AscL1

Background: This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.,ASCL1,ASH1,HASH1,MASH1,bHLHa46,AscL1,Epigenetics & Nuclear Signaling,Transcription Factors,Neuroscience,AscL1

Molecular Weight: 25kDa

Gene ID: 429

UniProt: P50553

Pathways: Dopaminergic Neurogenesis