ATP11C antibody (AA 430-650)

Catalog No. ABIN7265757

Product Details anti-ATP11C Antibody

Target: ATP11C (ATPase, class VI, type 11C (ATP11C))

Binding Specificity: AA 430-650

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP11C antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: ATP11C Rabbit pAb

Sequence: DGHKYKGVTQ EVDGLSQTDG TLTYFDKVDK NREELFLRAL CLCHTVEIKT NDAVDGATES AELTYISSSP DEIALVKGAK RYGFTFLGNR NGYMRVENQR KEIEEYELLH TLNFDAVRRR MSVIVKTQEG DILLFCKGAD SAVFPRVQNH EIELTKVHVE RNAMDGYRTL CVAFKEIAPD DYERINRQLI EAKMALQDRE EKMEKVFDDI ETNMNLIGAT A

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 430-650 of human ATP11C (NP_775965.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ATP11C

Target: ATP11C (ATPase, class VI, type 11C (ATP11C))

Alternative Name: ATP11C (ATP11C Products)

Synonyms: A330005H02Rik antibody, AI315324 antibody, Ig antibody, Atp11c-ps1 antibody, RGD1564481 antibody, ATPase, class VI, type 11C antibody, ATPase phospholipid transporting 11C antibody, Atp11c antibody

Background: Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids, phosphatidylserines (PS and phosphatidylethanolamines (PE, from the outer to the inner leaflet of the plasma membrane. Major PS-flippase in immune cell subsets. In erythrocyte plasma membrane, it is required to maintain PS in the inner leaflet preventing its exposure on the surface. This asymmetric distribution is critical for the survival of erythrocytes in circulation since externalized PS is a phagocytic signal for erythrocyte clearance by splenic macrophages. Required for B cell differentiation past the pro-B cell stage (By similarity. Seems to mediate PS flipping in pro-B cells (By similarity. May be involved in the transport of cholestatic bile acids (By similarity.,ATP11C,ATPIG,ATPIQ,Signal Transduction,Endocrine & Metabolism,Immunology & Inflammation,ATP11C

Molecular Weight: 126kDa/128kDa/129kDa

Gene ID: 286410

UniProt: Q8NB49