ATP1A3 antibody (AA 1-60)

Catalog No. ABIN7265770

Product Details anti-ATP1A3 Antibody

Target: ATP1A3 (ATPase, Na+/K+ Transporting, alpha 3 Polypeptide (ATP1A3))

Binding Specificity: AA 1-60

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP1A3 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: ATP1A3 Rabbit pAb

Sequence: MGDKKDDKDS PKKNKGKERR DLDDLKKEVA MTEHKMSVEE VCRKYNTDCV QGLTHSKAQE

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-60 of human ATP1A3 (NP_689509.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ATP1A3

Target: ATP1A3 (ATPase, Na+/K+ Transporting, alpha 3 Polypeptide (ATP1A3))

Alternative Name: ATP1A3 (ATP1A3 Products)

Synonyms: AHC2 antibody, DYT12 antibody, RDP antibody, Atpa-2 antibody, Atpa1a3 antibody, ATPa1a3 antibody, atp[a]3A antibody, cb706 antibody, fj35g11 antibody, wu:fj35g11 antibody, wu:fq14g09 antibody, atp[a]3B antibody, cb705 antibody, wu:fj56a06 antibody, ATPase Na+/K+ transporting subunit alpha 3 antibody, ATPase, Na+/K+ transporting, alpha 3 polypeptide antibody, ATPase, Na+/K+ transporting, alpha 3 polypeptide L homeolog antibody, ATPase, Na+/K+ transporting, alpha 3b polypeptide antibody, ATPase, Na+/K+ transporting, alpha 3a polypeptide antibody, ATP1A3 antibody, Atp1a3 antibody, atp1a3.L antibody, atp1a3b antibody, atp1a3a antibody

Background: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,ATP1A3,AHC2,ATP1A1,CAPOS,DYT12,RDP,Signal Transduction,Endocrine & Metabolism,Neuroscience,ATP1A3

Molecular Weight: 111kDa/113kDa

Gene ID: 478

UniProt: P13637

Pathways: Thyroid Hormone Synthesis, Proton Transport, Ribonucleoside Biosynthetic Process