BMP6 antibody

Catalog No. ABIN7265900

Product Details anti-BMP6 Antibody

Target: BMP6 (Bone Morphogenetic Protein 6 (BMP6))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This BMP6 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: BMP6 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human BMP6

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BMP6

Target: BMP6 (Bone Morphogenetic Protein 6 (BMP6))

Alternative Name: BMP6 (BMP6 Products)

Synonyms: BMP6 antibody, zgc:113595 antibody, vgr antibody, vgr-1 antibody, vgr1 antibody, VGR antibody, VGR1 antibody, D13Wsu115e antibody, Vgr1 antibody, bone morphogenetic protein 6 antibody, bone morphogenetic protein 6 S homeolog antibody, BMP6 antibody, bmp6 antibody, bmp6.S antibody, Bmp6 antibody

Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016],VGR, VGR1,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cell differentiation,Cytoskeleton,ESC Pluripotency and Differentiation,Extracellular Matrix,Extracellular Matrix_Bone,Growth factors,Immunology & Inflammation,NF-kB Signaling Pathway,Signal Transduction,Stem Cells,Wnt/β-Catenin Signaling Pathway,BMP6

Molecular Weight: 42kDa

Gene ID: 654

UniProt: P22004

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process